well around 200 substats is a good start, usually u can get 2 substats with 200 points with a good amount of defense and since u dont rlly spec into pvp or pve, just go for whatever i guess, even if u still do, mostly same advice
if u want a more theory crafting build (since we dont know how good life steal is), this is the build i plan to run
this is what im planning (basically the same as yours but enchants and modifiers swapped), but probably gonna wait to see if any new regen gear gets added in full release before investing it in early
around 100 is average (especially for non-sunken/drawback/insanity builds), around 120 is good typically through expensive builds or ones that lack defense/substats, 140+ is glass cannon territory because you can’t reach it with any methods other than using lower defense/substats